Allergy shots will often sting or itch for a while afterward, especially when the dosage starts to increase. Sometimes you will develop a large bump, like a giant mosquito bite. As long as it goes away within 24 hours, and you are not having trouble breathing or swallowing, you are probably fine. Most clinics have a number you can call with questions if you are concerned.

See if the nurse can use some topical spray and/or apply an ice pack right after you get the shot to help. Also, taking an anti-histamine like Zyrtec a short time before you get your shot helps reduce the reaction too. (Before taking any medication, please check with the doctor or nurse.)

My dr followed mine up with a dose of benadryl because I complained that it burned and itched so bad….

Sometimes mine did that especially if I came in contact with something I was allergic to - like pollen. I found that ice helps or a cold can of soda and the doctor gave me a benedryl cream to use that helped.